Downtown West Vacations from $381

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Your Downtown West Vacation

Downtown West is beckoning! Whatever type of getaway you're organizing, you can experience and see more of this neighborhood with a Downtown West vacation package. Your trip to Downtown West wouldn't be complete without exploring popular attractions nearby such as Busch Stadium, Gateway Arch and Dome at America’s Center. Whatever your travel goals or budget, booking a perfect Downtown West vacation is easy with Expedia.

The Latest Downtown West Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Elimwood Hotel, a Ramada by Wyndham
The Wildwood Hotel
The Cheshire
Remodeled and Inviting Free EV
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Where to stay in Downtown West

Find the best Downtown West areas and neighborhoods for the activities you enjoy most. Learn more about Downtown West

Downtown West Hotel Deals

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $122 total per night from Nov 15 to Nov 16
$122 total
Nov 15 - Nov 16
Total with taxes and fees
Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Nov 29 to Nov 30
$173 total
Nov 29 - Nov 30
Total with taxes and fees
21C Museum Hotel St Louis
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $134 total per night from Nov 15 to Nov 16
$134 total
Nov 15 - Nov 16
Total with taxes and fees
9.4/10 Exceptional! (1,614 reviews)
"Parking garage for a 20-ish dollar fee was awesome! Great breakfast buffet and dinner/cocktail time."

Reviewed on Nov 9, 2026

Drury Plaza Hotel St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Downtown West attractions

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.